Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity linked to bortezomib, a proteasome inhibitor Employed in the procedure of many myeloma. Its synthesis or examine is critical for ensuring the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor while in the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets unique different types of cancer, including Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their review is very important for optimizing the manufacturing system and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the therapy of breast most cancers. Several intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal 4S)-3-Hydroxy-4-phenyl-2-azetidinone cancer and compact mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have various applications, which includes antiviral Houses.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be used in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate in the synthesis of canagliflozin, a medication used to deal with style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).